New treatment options for inflammatory bowel diseases
نویسندگان
چکیده
منابع مشابه
New strategies for the treatment of inflammatory bowel diseases
Anti-TNF therapy is the most important treatment for inflammatory bowel disease patients. However, primary nonresponders are frequent and clinical recurrence under maintenance therapy is reported in 40% of the treated patients. The aim of this article is to explain the most important targets for the future of treatments in inflammatory bowel disease and to report the results of these news drugs...
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ulcerative colitis (uc) and crohn's disease (cd) are chronic inflammatory bowel diseases with uncertain etiology thought to be triggered by interactions between various environmental, genetic and immunologic factors. incidence rate of cd and uc is different in various geographic areas around the world, between 0.1-11 and 0.5-24.5 per 100,000 people for cd and uc, respectively. recent studies in...
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Inflammatory bowel disease (IBD) mainly comprises Crohn ’ s disease and ulcerative colitis and is considered an idiopathic disease affecting the entire gastrointestinal tract. Various approaches have been proposed for the treatment of IBD, but the development of an appropriate delivery system to specifically target different sites of inflammation in the gut has remained a challenge. The therape...
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The inflammatory bowel diseases have undergone an explosion of discovery in the last 10 years. The overwhelming focus of this has been in genetics and immune mechanisms of disease. While the former has provided critical information on predisposing factors, the latter has resulted in a panoply of novel immune-based therapies and technologies. These range from an improved approach to the use of c...
متن کاملCould platelet indices be new biomarkers for inflammatory bowel diseases?
BACKGROUND AND AIM Ulcerative colitis (UC) and Crohn's disease (CD) are chronic inflammatory diseases. Many serum biomarkers have been studied for diagnosis and monitoring of disease activity in inflammatory bowel diseases (IBD). Platelets play an important role in inflammation. The aim of the present study is to determine whether platelet indices; mean platelet volume (MPV), platelet distribut...
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ژورنال
عنوان ژورنال: Journal of Gastroenterology
سال: 2018
ISSN: 0944-1174,1435-5922
DOI: 10.1007/s00535-018-1449-z